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 CASE REPORT
Year : 2003  |  Volume : 40  |  Issue : 3  |  Page : 116-117

Primary plasma cell leukemia occuring in the young


1 Medical College Hospital, Thiruvananthapuram - 695 011, India
2 Dept of Medical Oncology, Rajiv Gandhi Cancer Institute & Research Centre, Rohini, Sector - 5, New Delhi 110085, India

Correspondence Address:
K Pavithran
Dept of Medical Oncology, Rajiv Gandhi Cancer Institute & Research Centre, Rohini, Sector - 5, New Delhi 110085
India
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Source of Support: None, Conflict of Interest: None


PMID: 14716116

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Plasma Cell Leukemia (PCL) is a rare form of plasma cell dyscrasia. Plasma cell leukemia has two variants: the primary form presents de novo in patients with no previous history of multiple myeloma (MM); the secondary form consists of a leukemic transformation in a previously recognized MM. In contrast to myeloma, PCL has an aggressive course. Median age at presentation is usually above 50 years. Here we report a case of primary PCL presenting at age of 21 years, which is extremely rare. She was treated with combination chemotherapy (VAD). Although she had a good response initially, later the disease progressed and she died 6 months after the diagnosis.






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