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Year : 2022  |  Volume : 59  |  Issue : 2  |  Page : 212-217

Factors predicting contralateral nodal spread in papillary carcinoma of thyroid

1 Department of Surgical Oncology, Tata Medical Center, Kolkata, West Bengal, India
2 Department of Head and Neck Surgery, Tata Medical Center, Kolkata, West Bengal, India

Correspondence Address:
Pattatheyil Arun
Department of Head and Neck Surgery, Tata Medical Center, Kolkata, West Bengal
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijc.IJC_684_19

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Background: Lymph node metastasis (LNM) is evident in about 20–50% of cases at presentation in papillary carcinoma thyroid (PTC). There are no clear recommendations for the need and extent of lateral and central compartment dissection in PTC. Methods: A total of 83 patients who underwent total thyroidectomy and bilateral selective neck dissection for diagnosed PTC from September 2011 to October 2017 were retrospectively analyzed. Results: Tumor site was bilobar or involving isthmus in 40 patients. Contralateral LNM was seen in 42 patients. Both radiological (median size 2.6 cm, P = 0.051) and pathological (median size 3.65 cm, P = 0.015) size of tumor, tumor involving isthmus or bilateral lobes (P = 0.006), and lymphovascular invasion (LVI) (P = 0.026) had significant correlation with contralateral LNM. Conclusion: Size and site of tumor, ipsilateral lateral compartment nodes involvement, and LVI status of tumor significantly increases the probability of contralateral LNM in patients of PTC.


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