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Year : 2022  |  Volume : 59  |  Issue : 2  |  Page : 288-294

Anticancer properties of melatonin and its role as an adjuvant in cancer treatment


Department of Anaesthesiology, Ibra Hospital, North Sharqiya Governorate, Ministry of Health-Oman, Ibra, Sultanate of Oman

Correspondence Address:
Abhijit Nair
Department of Anaesthesiology, Ibra Hospital, North Sharqiya Governorate, Ministry of Health-Oman, Ibra
Sultanate of Oman
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijc.IJC_1197_20

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Melatonin is an important hormone secreted from the pineal gland that mediates several biological functions in humans through circadian rhythm. The multimodal properties of melatonin when administered systemically have generated a lot of interest among researchers. The anticancer properties of melatonin per se and its importance in cancer patients when used as an adjunct to ongoing chemotherapy and radiotherapy have led to tremendous research in animals and humans with encouraging results. The present write-up discusses the current evidence of using melatonin as an adjunct in hormone-dependent and hormone-independent cancers.






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