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Consensus guidelines on management of oral potentially malignant disorders

1 Department of Oral Medicine and Radiology, KLE Society's Institute of Dental Sciences; Oral Cancer Screening Program, Biocon foundation, Bengaluru, Karnataka, India
2 Healthcare, Biocon Foundation, Bengaluru, Karnataka, India
3 Oral Medicine and Experimental Pathology, King's College London, England
4 Department of Oral Medicine and Radiology, KLE Society's Institute of Dental Sciences, Bengaluru, Karnataka, India
5 Department of Radiation Oncology, B.R. Ambedkar Institute Rotary Cancer Hospital, AIIMS, Delhi, India
6 Department of Surgical Oncology, Tata Memorial Center, Mumbai, Maharashtra; Center for Cancer Epidemiology, Tata Memorial Center, Mumbai, International Federation of Head and Neck Oncologic Societies, Bengaluru, Karnataka, India
7 Strands Life Sciences, Bengaluru, Karnataka, India
8 Community Oncology, Regional Cancer Center, Trivandrum, Kerala, India
9 Department of Medical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India
10 Head and Neck Oncology, Mazumdar Shaw Cancer Center, Bengaluru, Karnataka, India
11 India Cancer Research Consortium, Rollins Institute of Public Health, Emroy University, Atlanta, GA, United States
12 PMS College of Dental Science and Research, Trivandrum, Kerala, India
13 Department of Oral Pathology and Microbiology, Faculty of Dental Sciences, Jazan University, Saudi Arabia
14 Indian Dental Association, Kerala, India
15 Biocon Foundation, India
16 Biocon Foundation, Bengaluru, Karnataka, India
17 Cochin Cancer Center, India

Correspondence Address:
Moni A Kuriakose,
Cochin Cancer Center
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijc.IJC_128_21

Oral cancer is usually preceded by oral potentially malignant disorders (OPMDs) and early detection can downstage the disease. The majority of OPMDs are asymptomatic in early stages and can be detected on routine oral examination. Though only a proportion of OPMDs may transform to oral squamous cell carcinoma (OSCC), they may serve as a surrogate clinical lesion to identify individuals at risk of developing OSCC. Currently, there is a scarcity of scientific evidence on specific interventions and management of OPMDs and there is no consensus regarding their management. A consensus meeting with a panel of experts was convened to frame guidelines for clinical practices and recommendations for management strategies for OPMDs. A review of literature from medical databases was conducted to provide the best possible evidence and provide recommendations in management of OPMDs.

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