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Figure 1: (a) Computed tomography chest shows a large anterior mediastinal mass along with bilateral patchy areas of consolidation; (b) Cut surface of anterior mediastinal mass having a variegated appearance with areas of haemorrhage; (c) Sections (40 × magnification) examined from anterior mediastinal mass shows near total effacement of nodal architecture; (d) Closer view (100 × magnification) with sheets of atypical cells having moderate to abundant eosinophilic cytoplasm; (e) (400 × magnification) These atypical cells have pleomorphic nuclei with many showing longitudinal grooving; (f) (400 × magnification) Mitotic figures were frequent. (All photographs are hematoxylin and eosin stained); (g) CD20 (Roche-Ventana, clone L26) immunohistochemistry (100 × magnification) highlights the B lymphocytes; (h) CD3 (Roche-Ventana, clone 2GV6) immunohistochemistry (100 × magnification) highlights the T lymphocytes; (i) CD68 (Dako, clone KP1) and (j) CD1a (Dako, clone 010) immunohistochemistry (100 × magnification) highlights the atypical langerhans cells

Figure 1: (a) Computed tomography chest shows a large anterior mediastinal mass along with bilateral patchy areas of consolidation; (b) Cut surface of anterior mediastinal mass having a variegated appearance with areas of haemorrhage; (c) Sections (40 × magnification) examined from anterior mediastinal mass shows near total effacement of nodal architecture; (d) Closer view (100 × magnification) with sheets of atypical cells having moderate to abundant eosinophilic cytoplasm; (e) (400 × magnification) These atypical cells have pleomorphic nuclei with many showing longitudinal grooving; (f) (400 × magnification) Mitotic figures were frequent. (All photographs are hematoxylin and eosin stained); (g) CD20 (Roche-Ventana, clone L26) immunohistochemistry (100 × magnification) highlights the B lymphocytes; (h) CD3 (Roche-Ventana, clone 2GV6) immunohistochemistry (100 × magnification) highlights the T lymphocytes; (i) CD68 (Dako, clone KP1) and (j) CD1a (Dako, clone 010) immunohistochemistry (100 × magnification) highlights the atypical langerhans cells