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Figure 3: (a) Capillary electrophoresis demonstrating BRAFV600E mutation in the index case by sanger sequencing; (b) Bone marrow (100 × magnification) with many pleomorphic atypical cells amidst macrophages showing evidence of hemophagocytosis (arrow); (c) Liver tissue (100 × magnification) with infiltration of sinusoids by atypical cells; (d) Duodenum with marked expansion (100 × magnification) of lamina propria and submucosa by atypical cells; (e) Lung tissue (100 × magnification) with interstitial widening by atypical cells; (All photographs are hematoxylin and eosin stained)

Figure 3: (a) Capillary electrophoresis demonstrating BRAFV600E mutation in the index case by sanger sequencing; (b) Bone marrow (100 × magnification) with many pleomorphic atypical cells amidst macrophages showing evidence of hemophagocytosis (arrow); (c) Liver tissue (100 × magnification) with infiltration of sinusoids by atypical cells; (d) Duodenum with marked expansion (100 × magnification) of lamina propria and submucosa by atypical cells; (e) Lung tissue (100 × magnification) with interstitial widening by atypical cells; (All photographs are hematoxylin and eosin stained)